to do something that is contrary to the usual way of doing things
कुछ ऐसा करना जो आमतौर पर किए जाने के तरीके से विपरीत हो (kuch aisa karna jo aamtaur par kiye jaane ke tareeke se vipreet ho)
"Their new approach really goes against the grain of traditional research methods."
"उनका नया दृष्टिकोण पारंपरिक शोध विधियों के खिलाफ जाता है।" (Unka naya drishtikon paaramparik shodh vidhiyon ke khilaaf jaata hai.)
no matter what happens; in any weather or situation
to get some sleep
to prepare to work hard or take on a challenge
a short nap or brief sleep
a situation in which virtue is rewarded and vice is punished...
The greater the risk, the greater the potential benefit.