to do something that is contrary to the usual way of doing things
"Their new approach really goes against the grain of traditional research methods."
a chance to live or start something again after a period of...
to move up in position or success, especially in a career
to be in a very difficult or challenging situation
to put pressure on someone to make them behave or act a cert...
to stay calm under stress or provocation
to try to teach someone something that is difficult for them...