to do something that is contrary to the usual way of doing things
物事の通常のやり方に反することをする (monogoto no tsūjō no yarikata ni hansuru koto o suru)
"Their new approach really goes against the grain of traditional research methods."
"彼らの新しいアプローチは、従来の研究方法に反しています。" (Karera no atarashī apurōchi wa, jūrai no kenkyū hōhō ni hanshiteimasu.)
very excited and happy about many options or things
to boast or brag about your achievements
to support your words with actions or financial commitment
to take an indirect route
an achievement to be proud of
no matter what happens; in any weather or situation