to have no more patience or strength left to deal with a problem
no tener más paciencia o fuerza para lidiar con un problema (no tener mas paciencia o fuerza para lidiar con un problema)
"She’s at the end of her rope trying to manage her work and family together."
"Ella está al final de su cuerda tratando de gestionar su trabajo y su familia juntas." (Ella esta **al final de su cuerda** tratando de gestionar su trabajo y su familia juntas)
to send a private message to someone on social media, often...
to dismiss or refuse something with a gesture or comment
to be responsible for a mistake or bad situation.
to deal with a difficult technological challenge
to have important or ambitious goals for the future
a series of events triggered by one event