I do not know the answer to a question
No sé la respuesta a una pregunta (no se la respuesta a una pregunta)
"I don't know what time the movie starts. Your guess is as good as mine."
"No sé a qué hora empieza la película. Tu suposición es tan buena como la mía." (no se a ke ora empiesa la pelicula tu suposicion es tan buena komo la mia)
you shouldn't form an opinion on someone or something based...
to miss an opportunity
Use your time effectively and make the most of every moment.
to bear the burden of an important duty or obligation
to continue progressing despite obstacles or setbacks
to rely on a single plan or source of success