to be so worried or stressed that you don’t know what to do
быть настолько обеспокоенным или напряженным, что не знаешь, что делать (byt' nastol'ko obespokoennym ili napryazhyonnym, chto ne znayesh', chto delat')
"I’m at my wits’ end trying to finish all this work."
"Я на грани своих возможностей, пытаясь закончить всю эту работу." (ya na grani svoikh vozmozhnostey, pytayas' zakonchit' vsyu etu rabotu)
succeeding after two failures
to reach an agreement or deal
to get all the attention, often taking it away from someone...
to begin to take effect
something that completely changes the way things are done
to say something embarrassing or inappropriate by mistake