despite great difficulties or challenges
несмотря на большие трудности или препятствия (nesmotrya na bolshie trudnosti ili prepyatstviya)
"She succeeded against all odds and became a doctor."
"Она добилась успеха, несмотря на все трудности, и стала врачом." (ona dobilas uspeha nesmotrya na vse trudnosti i stala vrachom)
to break someone's confidence in you
a report confirming good health
having positive prospects or possibilities
to destroy relationships or connections permanently
in a safe or stable situation
to relax and stop being angry or nervous
