to make a significant discovery or achievement
hacer un descubrimiento o logro significativo (hacer un descubrimiento o logro significativo)
"She made a breakthrough in her research that could change the field."
"Ella hizo un gran avance en su investigación que podría cambiar el campo." (ella hizo un gran avance en su investigacion que podria cambiar el campo)
generally speaking; on the whole
a person who is the first to do something innovative
to manage even when something is missing
Have confidence; believe in your ability.
to be on time for a train or event
at the most advanced position in a field